WARNING
Compounded medications are not FDA-approved or evaluated for safety or efficacy but include active ingredients sourced from FDA-registered facilities. If you notice any changes in the appearance, color, or consistency of the medication, please contact your prescriber immediately before using it.

Do not use this medication if you are or suspect you may be allergic to any of the ingredients in the compounded product. Other ingredients include:

• Disodium phosphate dihydrate
• Benzyl alcohol
• Hydrochloric acid
• Sodium hydroxide

Please contact your doctor ASAP and seek in-person care immediately if a side effect becomes problematic or you experience:

• Severe nausea and/or vomiting resulting in dehydration: It is important to stay well hydrated and drink plenty of fluids while on this medication.
• Kidney problems/kidney failure: Vomiting, nausea, diarrhea can cause dehydration and kidney issues and make kidney problems worse in individuals who have pre-existing kidney conditions; may sometimes lead to the need for hemodialysis.
• Thyroid C-Cell Tumor: Trouble swallowing, hoarseness, a lump or swelling in your neck, or shortness of breath (see “Black Box Warning”).
• Pancreatitis: Severe pain in your abdomen or back that will not go away.
• Acute gallbladder disease: Pain in the middle or right upper stomach, fever, white parts of your eyes turn yellow or skin turns yellow, nausea/vomiting. If gallstones or inflammation of the gallbladder is suspected further studies are needed.
• Hepatitis, elevated liver enzymes, or jaundice.
• Diabetic retinopathy problems: Changes in vision in those with type 2 diabetes, particularly vision problems may worsen in those with a history of diabetic retinopathy.
• Severe gastrointestinal disease: May cause gastrointestinal disease; do not use if you have a history of severe gastrointestinal disease.
• Signs of low blood sugar (for example, dizziness, weakness, shakiness, jitteriness, headache, anxiety/mood changes, rapid heartbeat, confusion, slurred speech, sweating, or lightheadedness): While this is rare with semaglutide, if it occurs, please seek in-person care immediately. If you have these symptoms, try having liquid or food containing sugar (around 15-20 grams)—drink juice or regular soda, or eat some hard candies right away, as this will help raise your blood sugar quickly. If taken with insulin or an insulin secretagogue (ie sulfonylureas), it is best to talk to your health care provider about possibly lowering the dose of these medications to lower the risk of hypoglycemia.
• Increasing heart rate.
• Worsening depression, behavior changes, or suicidality.
• Never reuse or share needles, syringes, or vials.

BLACK BOX WARNING:
Name brand semaglutide carries a Black Box Warning.

Semaglutide is not recommended in individuals with a history of medullary thyroid carcinoma, a family history of such, or in patients with multiple endocrine neoplasia syndrome type 2. Do not take it if you have ever had thyroid cancer. In studies with rodents, semaglutide caused thyroid tumors, including thyroid cancer; it is not known if it will cause thyroid tumors or cancer in humans. Please notify your doctor ASAP if you develop trouble swallowing, hoarseness, a lump or swelling in your neck, or shortness of breath.

If you experience a medical emergency, call 911 or go to the nearest emergency room.

Tell your health care provider about your medical history prior to taking semaglutide.

Avoid alcohol while taking this medication. If you’re taking diabetes medications, please discuss this with your prescribing doctor before starting semaglutide, as your diabetes medications may need to be adjusted as you lose weight.

Use adequate contraception while taking this medication. Do not take this medication if pregnant, trying to get pregnant or breastfeeding. If you plan to become pregnant, this medication needs to be stopped at least 2 months before trying. This medication may cause fetal harm.

Notify your doctor if you have kidney, liver, or pancreas problems.

Stop using semaglutide and call your health care provider immediately if you have severe stomach or abdomen pain that will not go away, with or without vomiting.

Stop using semaglutide and get medical help right away if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue, or throat; problems breathing or swallowing; severe rash or itching; fainting or feeling dizzy; or very rapid heartbeat.

Serious hypersensitivity reactions (e.g., anaphylaxis and angioedema) have been reported. Discontinue semaglutide if suspected and promptly seek medical advice.